A right-handed outfielder and pitcher, Wilber signed a free agent contract with the Detroit Tigers in 1978 and played two years in their farm system. He also played in the farm system of the Oakland Athletics. In 1978, Wilber joined the Paintsville Hilanders, the Tigers farm club in the Appalachian League in Paintsville, Kentucky. In 1979, he played for the Lakeland Tigers in the Florida State League. Later that year, he wrapped up his minor league career with the Medford A’s, the Oakland Athletics farm team in Medford, Oregon.

Wilber played three seasons for St. Louis University High School. He received a four-year baseball scholarship to the University of Southern Illinois at Edwardsville. He played center field for the SIUE Cougars from 1975 to 1979, helping his team advance to the College World Series in 1976 and 1977. He hit a key home run in the NCAA Finals to send the Cougars to the 1977 College World Series. The 1976 team and the 1977 team were both inducted into the SIUE Athletics Hall of Fame.

During the summers of 1975 and 1976, Wilber was a center fielder for SIUE in the St. Louis MO-IL Collegiate Baseball Instructional League. He batted .406 in 1976 and led his team in every hitting statistic.

Wilber played semi-pro ball in the summer of 1977 for the Cheney Studs in Seattle, and the Danville Roosters in the Central Illinois Collegiate League. He hit .363 for Danville in a strong league with many future Major Leaguers like Andy McGaffigan and Charlie Leibrandt.

In 1984, Wilber joined the Sauget Wizards in the Mon-Clair League and played six seasons. He was with the Wizards from 1984 to 1986 and then again in 1988 and 1989. He returned to the Wizards in 1992 as a player-manager. He was voted MVP in 1985. The Wizards won the Mon-Clair League Championship in 1988. Wilber helped the Wizards defeat Team USA. In 1992, the Wizards won the Valmeyer Fourth of July Tournament. That year, he was a player-manager in the Mon-Clair League all-star game.

In 1987, he played semi-pro ball while working in the District of Columbia. His Fairfax team was crowned the Eastern Seaboard Champion. Fairfax defeated the Korean National team.

From 1980 to 1984, Wilber was a professional baseball scout for the Toronto Blue Jays. He covered six Midwest states and also traveled to California and Florida. His greatest discovery was Mike Henneman of St. Charles who pitched in the Major Leagues for ten years.

In 1980, Wilber was a coach for the Blue Jays farm team in Utica, New York. Wilber was an executive with the Major Indoor Soccer League. He was Vice President of the St. Louis Storm and General Manager of the Kansas City Attack indoor soccer club. His father was Cardinal catcher Del Wilber who played in the Major Leagues for eight years.